Lab Tests: If you have symptoms of ACC, your doctor will order lab tests of your urine and blood to check your hormone levels. Males may have abnormal penis growth or early puberty changes like increased muscle growth and body hair. Females may have an overgrowth in female genitalia and facial hair. Other symptoms of ACC are different for females and males, since it can change hormone levels. How is adrenocortical carcinoma diagnosed?ĪCC can cause pain in the abdomen, high blood pressure, acne, overgrowth of hair, and voice deepening. How common is adrenocortical carcinoma?ĪCC is very rare, affecting around one case diagnosed in one million people in the US. A functioning ACC tumor often makes too much of the hormones cortisol, aldosterone, testosterone, or estrogen. ACCs form in the adrenal cortex.Īn ACC may be functioning, which means it makes more hormone than normal, or non-functioning, which means it has no effect on hormone production. The adrenal cortex makes important hormones that help your body control water balance, blood pressure, stress response, and cause the body to have male or female traits. The outside of these glands is called the adrenal cortex. You can help speed up the development of new treatments by giving researchers the tools they need.Īdrenocortical carcinoma, or ACC, is a cancer of the adrenal glands, which are two small triangular-shaped glands that sit on top of each kidney.
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